Ngoana oa hao o ile a kula, 'me ngaka e ile ea fana ka teko ea tlhahlobo ea mali. Ho latela liphello tsa hae, ho ile ha e-ba le mali a ngoana a ekelitseng boemo ba alkaline phosphatase. Batsoali, ha e le hantle, ba potlakela ho ipotsa hore na alkaline phosphatase e ikarabella hokae le hore na ke eng e bontšang hore na ke eng.
Alkaline phosphatase e bontša eng?
Alkaline phosphatase ke sehlopha sa lik'hemik'hale tse nang le lik'hemik'hale tsohle tsa 'mele oa motho. Boholo ba phosphatase ea alkaline e fumanoa mahetleng a masapo, li-osteoblasts, li-ducts tsa bile. Moqolo o moholo o tlalehoa ke 'mala oa mala. Alkaline phosphatase e hlahisoa ke karolo ea kahare ea intestinal mucosa, empa e nka karolo feela ka ts'ebetso ea ho tšela lijo ka lekhetlo la bobeli. Mosebetsi o ka sehloohong oa alkaline phosphatase ke phallo ea phosphoric acid, e leng e hlokahalang bakeng sa 'mele, ho tloha mefuteng e sa tšoaneng ea metsoako. Enzyme ena e boetse e thusa ho tsamaisa phosphorus ho pholletsa le 'mele.
Lintho tse latelang tsa alkaline phosphatase ho bana li nkoa e le tse tloaelehileng:
- ha a hlaha -
- ka letsatsi la bohlano ka mor'a tsoalo -
- ho tloha matsatsing a 6 ho isa ho likhoeli tse 6 -
- ho tloha likhoeli tse 6 ho isa ho 1 selemo -
- ho tloha selemo se seng ho ea ho lilemo tse tharo -
- ho tloha ka lilemo tse 4 ho ea ho tse 6 -
- ho tloha ka lilemo tse 7 ho ea ho tse 12 -
- ho tloha ho lilemo tse 13 ho ea ho tse 17 (bashanyana) -
- ho tloha ho lilemo tse 13 ho ea ho tse 17 (banana)
Lipalo tsa enzyme ena serum ea mali e ka 'na ea fapana hanyane ho ea ka mekhoa ea lipatlisiso le li-reagents tse sebelisitsoeng.
Ketsing ea bana, tlhahlobo ea lik'hemik'hale tsa alkaline phosphatase e phetha karolo ea bohlokoa ho fumanoeng lefu la sebete, le ho fokotseha ha bile ho phallela ho duodenum. Tabeng ena, alkaline phosphatase maling a ngoana hangata a eketseha. Boemo bo phahameng ka ho fetisisa ba phosphatase bo etsahala ha ho e-na le tlōlo ea ho tsoa ha bile ka lebaka la majoe a lebenkeleng la bile kapa li-tumor tsa ducts. Ho phaella moo, ka alkaline phosphatase ho ngoana, ngaka e ka boela ea beha lits'oaetso tse joalo:
- mafu a masapo, ho akarelletsa le lihlahala, sarcoma, metastase ea kankere meleng;
- hyperparathyroidism;
- ho hlōloa ha masapo ka lymphogranulomatosis;
- rickets;
- Lefu la Paget (lefu la sekoti);
- tšoaetso ea mononucleosis;
- myeloma;
- cytomegaly ea bana;
- tšoaetso ea mala.
Ntho ea bohlokoa ka ho fetisisa ke pontšo ea alkaline phosphatase ho bana bakeng sa ho hlahlojoa kapele ho rickets. Tabeng ena, ts'ebetso ea enzyme e phahama nako e telele pele matšoao a meriana a lefu lena a hlaha.
Ka linako tse ling ho na le lintho tsa tlhaho, ke hore, tlhaho, keketseho ea boemo ba alkaline phosphatase ho seramu ea mali: masea a sa le monyenyane kapa lilemong tsa bocha nakong ea bokhachane le khōlo e matla ea mesifa ea masapo.
Ha o sebelisa lithethefatsi tse nang le phello ea lehlakoreng la hepatotoxic, tekanyo ea enzyme ea alkaline phosphatase ho ngoana e ka boela ea phahama. Lithethefatsi tsena li kenyelletsa paracetamol, penicillin, sulfonamide, erythromycin le tse ling tse ngata. Ka metabolism e eketsehileng linthong tsa masapo nakong ea ho phatloha ha mesifa ea masapo, boemo ba enzyme ena bo boetse bo phahame.
Ho fokotsa boemo ba enzyme ea alkaline phosphatase ha bo bohlokoa haholo tleleniking. Ho fokotsa boemong ba enzyme e ka ba le tlōlo e fapaneng ea masapo, ho hloka lijo ka zinki, magnesium, vithamine C le B12, ka mali a phokolo ea mali le hypothyroidism, ka
Joang ho fokotsa alkaline phosphatase?
E le hore ho be le lintlha tsa alkaline phosphatase litekanyetso ho ngoana hore a khutle ho tloaelehileng, ho hlokahala hore ho phekoloe lefu lena le ka sehloohong, eseng feela ho fetola boemo bona ho tloaelehileng.
Bana, mosebetsi oa alkaline phosphatase o phahame ho feta batho ba baholo. Maemong a mang, ts'ebetso e ntseng e eketseha ea phosphatase ke eona feela pontšo ea lefu le kotsi la sebete. Ka hona, ke habohlokoa haholo ho etsa lithuto tsohle tsa tlhokomelo ea litliniki le ho qala phekolo ea ngoana oa hao ka nako, e leng se tla lebisa ho phomola ka potlako.