Likokoana-hloko tse bakang maloetse le libaktheria li fetoha sesosa sa mafu a maholo a tsamaiso ea ho hema, tsamaiso ea urogenital le likarolo tse ling tsa 'mele. Fluoroquinolones ea moloko oa morao-rao ka katleho o ba hanyetsa. Lithethefatsi tsena tse thibelang likokoana-hloko li khona ho hlōla esita le tšoaetso e hanyetsanang le quinolones le fluoroquinolones, e sebelisitsoeng lilemong tse 'maloa tse fetileng.
Fluoroquinolones 4 meloko - ke mofuta ofe oa lithethefatsi?
Fluoroquinolones e 'nile ea sebelisoa ho laola likokoana-hloko ho tloha lilemong tsa bo-1960, nakong eo baktheria e neng e bonahala e sa sireletsehe ho meriana ena e mengata. Ke ka lebaka leo bo-rasaense ba sa emeng moo 'me ba hlahisa lithethefatsi tse ncha le tse ncha, ho eketsa katleho ea bona. Mona ke mabitso a li-fluoroquinolone tsa moloko oa ho qetela le ba pele ho tsona:
- Litokisetso tsa moloko oa pele (nalidixic acid, oxolinic acid).
- Dithethefatsi tsa bobeli (lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iprofloxacin).
- Litokisetso tsa moloko oa boraro (levofloxacin, parfloxacin).
- Litokisetso tsa moloko oa bone (moxifloxacin, hemifloxacin, gatifloxacin, sitafloxacin, trovafloxacin).
Ketso ea moloko o mocha oa fluoroquinolones e itšetlehile ka ho kenngoa ha bona ka DNA ea baktheria, moo likokoana-hloko li lahleheloang ke bokhoni ba ho ata le ho shoa ka potlako. Ka moloko o mong le o mong, palo ea bacilli khahlanong le lithethefatsi e atlehang e eketsa. Ho fihlela joale, sena ke:
- E. coli;
- Pseudomonas aeruginosa ;
- thupa ea gnofilnaya;
- shigella;
- salmonella;
- k'holera;
- hominococci;
- meningococci;
- Campylobacter;
- chlamydia;
- mycoplasma;
- pneumococci;
- staphylococci .
Ha ho makatse hore ebe fluoroquinolones e mengata e le lethathamong la meriana ea bohlokoa ka ho fetisisa le e hlokahalang - ntle le bona ho ke ke ha khoneha ho tšoara pneumonia, k'holera, lefuba le mafu a mang a kotsi. Likokoana-hloko feela tseo mofuta ona oa meriana o ke keng oa li ama ke libaktheria tsohle tsa anaerobic.
Fluoroquinolones ke eng ka matlapa?
Ho fihlela joale, matlapa a fanoa ka ho phefumoloha fluoroquinolones ho loantša mafu a holimo le a tlaase a phefumoloho, lithethefatsi bakeng sa ho phekoloa ho tšoaetsoa ha genito-urinary le
- Levofloxacin;
- Moxifloxacin;
- Sparfloxacin;
- Norfloxacin le ba bang.
Pele u qala kalafo, hlahloba ka hloko li-contraindications - meriana e mengata ea sehlopha sena ha e khothalletsoe bakeng sa tšebeliso ea ho sebelisa lipepere, liphio le sebete. Bakeng sa bana le bakhachane, fluoroquinolone e bonts'oa ka mokhoa o tiileng ho ea ka ngaka ea ngaka mabapi le ho boloka bophelo.